This is the TL:DR version of my previous post.
After installing [MacPorts](http://www.macports.org/install.php) via the package installer, open a terminal session and enter the following:
% sudo port selfupdate
% sudo port install python27
% sudo port install py27-numpy
% sudo port install py27-scipy
% sudo port install py27-matplotlib
% sudo port install py27-nltk
% sudo port install python_select
% sudo port select –set python python27
By the way, once I did all this. I was able to run a Python script that relied on `matplotlib` to run. *Sweet.*
Complete MacPorts Installation Cheat Sheet – John Laudun
MacPorts Weirdness: NLTK for Python 3 Depends on Python 2 – John Laudun